Journal of Agricultural Science and Food Research
Open Access
ISSN: 2593-9173
+44 1223 790975
ISSN: 2593-9173
+44 1223 790975
Bedor El- Ahmary
Saudi Arabia
Research Article
Mitigating Effect of Ginger against Oxidative Stress Induced by Atrazine Herbicides in Mice Liver and Kidney
Author(s): Nahla S. EL- Shenawy, Bedor El- Ahmary and Rasha A. Al- EisaNahla S. EL- Shenawy, Bedor El- Ahmary and Rasha A. Al- Eisa
Pesticide chemicals may induce oxidative stress leading to generation of free radicals and alterations in antioxidants or oxygen free radical (OFR) scavenging enzymes. Hence, the effect of sub-chronic atrazine (2-chloro-4-ethylamino-6- isopropylamino-1,3,5-triazine) exposure was evaluated on lipid peroxidation, antioxidant power, glutathione and OFR scavenging enzymes in albino mice. Experimental animals were administered atrazine (1/8 LD50) and/or ginger (120 mg/ kg body weight, each alternative day) intraperitoneally for 14 days. There was higher level of malondialdehyde in liver and not in kidney of mice treated with atrazine than control animals. Superoxide dismutase and catalase activities were decreased in liver and kidney tissue in atrazine-treated animals compared to the control. A highly significant increase in glutathione-S-transferase activity was observed in liver of treat.. View More»
DOI:
10.4172/2155-6202.1000107