Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
+44 1300 500008
ISSN: 2167-0412
+44 1300 500008
William H Witola
College of Veterinary Medicine,
Urbana-Champaign, 2001 South Lincoln Avenue, Urbana, IL 61802
Tanzania
Short Communication
Activity of Green Algae Extracts against Toxoplasma gondii
Author(s): Jonathan L Powersa, Xuejin Zhang, Chi Yong Kim, Daniel A Abugrib and William H WitolaJonathan L Powersa, Xuejin Zhang, Chi Yong Kim, Daniel A Abugrib and William H Witola
Toxoplasma gondii is a zoonotic protozoa of economic significance in livestock. Infected livestock meat and products act as a source of T. gondii infection in humans. Current drugs against T. gondii are limited by hypersensitivity and toxicity, and are not effective against the encysted bradyzoite stage of T. gondii. Thus, there is urgent need for safe and effective therapeutic agents against T. gondii. Marine algae possess potent antifungal and antibacterial properties, but there are no reports on its anti-protozoal activity. Therefore, in this study we obtained nhexane and methanol extracts of green algae (Chlorophyceae) and analyzed their content by high performance liquid chromatography coupled with mass spectrometry, as well as tested their in vitro anti-Toxoplasma activities. Compared to the n-hexane extract of Chlorophyceae, the methanol extract contained higher content of flav.. View More»
DOI:
10.4172/2167-0412.1000293