Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
ISSN: 2167-0412
Washington D
Tanzania
Research Article
Effect of Momordica Charantia on the Cytotoxic and Virulence Responses of Campylobacter Jejuni Isolated from Poultry Fecal Samples
Author(s): Khatiwada J, Kallur V, Mentreddy S, Davis S, Washington D, Smith D and Williams LKhatiwada J, Kallur V, Mentreddy S, Davis S, Washington D, Smith D and Williams L
Consumption of untreated drinking water, raw milk, undercooked poultry meat and handling of raw poultry meat are the main sources of campylobacteriosis. Treatment of campylobacteriosis becomes very difficult due to the increasing pattern of antimicrobial resistance of these microbes. Thus, objectives of this study were to determine the cytotoxic potential of Campylobacter jejuni (C. jejuni) isolated from fecal samples of poultry on Chinese Hamster Ovary cell (CHO) and also to determine the effect of Bitter Melon (Momordica charantia) extract (BME) at 25%, 5%, 2.5% and 0.5% concentrations to reduce the cytotoxic effect of C. jejuni on CHO cells. Thirty-two C. jejuni strains isolated from poultry fecal samples were analyzed using Bolton broth as pre-enrichment broth and modified Charcoal–Cefoperazone Deoxycholate agar as a selective media, then characterized for the presence of 16.. View More»
DOI:
10.4172/2167-0412.1000117