Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
+44 1300 500008
ISSN: 2167-0412
+44 1300 500008
Tiwalade Adewale Olugbade
Ile-Ife, 220005 Osun-State
Nigeria
Research Article
Acetylcholinesterase Inhibitory Effect and Characterization of the Essential Oil of Plectranthus aegyptiacus (Forssk.) C. Chr. Growing in Nigeria
Author(s): Christianah Abimbola Elusiyan, Idowu Olawuni, Tiwalade Adewale Olugbade, Omolara Orafidiya and Armando McDonaldChristianah Abimbola Elusiyan, Idowu Olawuni, Tiwalade Adewale Olugbade, Omolara Orafidiya and Armando McDonald
Essential oil of fresh leaves of Plectranthus aegyptiacus (Forssk.) C. Chr. collected in Nigeria was analyzed to determine its chemotype. A total of 30 compounds were identified. Constituents identified were mainly mono and sesquiterpenoids with the major components, accounting for about 76% of the components, being α-terpinene (6.9%), p-cymene (14.2%), γ-terpinene (5.5%), carvacrol (10.0%), α-copaene (5.3%), α-caryophyllene (5.8%), germacrene-D (11.6%), δ-cadinene (8.4%) and α-cadinol (8.4%). The essential oil showed anticholinesterase inhibitory activity with an IC50 of 8.29 ± 0.67 mg/ml... View More»
DOI:
10.4172/2167-0412.1000316