Medicinal & Aromatic Plants

Medicinal & Aromatic Plants
Open Access

ISSN: 2167-0412

Shakour ZTA

Shakour ZTA
Laboratory of Phytochemistry, National Organization for Drug Control and Research,
Cairo 11364

  • Research Article
    Chemical Composition and Antibacterial Activity of Volatile Oil of Sequoia sempervirens (Lamb.) Grown in Egypt
    Author(s): Taha KF and Shakour ZTATaha KF and Shakour ZTA

    The hydrodistilled essential oil of leaves of Sequoia sempervirens (Lamb.) belonging to family Cupressaceae was analyzed by GC/MS. Thirty six compounds were identified representing 95.62% of the total oil containing α-phellandrene (29.60%), dl-limonene (15.60%), α-pinene (8.65%) and terpinene-4-ol (3.5%) as major components. The studied essential oil showed a dose-dependent antioxidant activity using 2, 2-diphenyl-1-picrylhydrazyl assay (IC50: 32.2 μg/mL). The antimicrobial activity of S. sempervirens leaves oil was screened against Gram-positive and Gram-negative bacteria and fungi. The strongest antibacterial effects of oil were on Bacillus subtilis, Trichophyton mentagrophytes and Staphylococcus aureus. S. sempervirens oil showed potent cytotoxic activity against the tested carcinoma cell lines; hepatocellular (HEPG2), colon adenocarcinoma (HCT-116) and breast (MCF7).. View More»
    DOI: 10.4172/2167-0412.1000245

    Abstract PDF

Relevant Topics