Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
ISSN: 2167-0412
Pierre Lutgen
Luxembourg
Research Article
Investigations of Artemisia Annua and Artemisia Sieberi Water Extracts Inhibitory Effects on Β-Hematin Formation
Author(s): Mutaz Akkawi, Suhair Jaber, Qassem Abu-Remeleh, Ogwang Patrick Engeu and Pierre LutgenMutaz Akkawi, Suhair Jaber, Qassem Abu-Remeleh, Ogwang Patrick Engeu and Pierre Lutgen
Malaria is the most prevalent infectious disease in the world, killing 1-2 million people each year. New drugs are urgently needed to treat drug-resistant strains of malaria. In a previous study we found that extracts from Salvia palestinia leaves inhibited the formation of β-hematin with efficiency similar to that of chloroquine. The objective of this study was to investigate the effect of other plant extracts on hemozoin formation. A comparison between the efficiency of aqueous extracts or infusions of Artemisia annua from Luxembourg and Artemisia sieberi from Palestine in inhibiting β-hematin formation was done. Although it was found that the Artemisia sieberi leaf tea infusion was less effective than that of the Artemisia annua, the stem infusion of Artemisia sieberi was found to be better than that of Artemisia annua stems. Results obtained with infusions prepared with .. View More»
DOI:
10.4172/2167-0412.1000150