Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
ISSN: 2167-0412
Jeronimo Facundo Torti
College of Medicine,
Mendoza
Argentina
Research Article
Hypoglycemic Effect due to Insulin Stimulation with Plantago major in
Wistar Rats
Author(s): Maria Angelica Abud, Andrea Liv Nardello and Jeronimo Facundo TortiMaria Angelica Abud, Andrea Liv Nardello and Jeronimo Facundo Torti
Background: Diabetes mellitus (DM) refers to a group of common metabolic disorders that share the phenotype of hyperglycemia, which causes secondary pathophysiological changes in multiple organ systems. Several times the Plantaginaceae family have been reported as crude drugs with hypoglycemic effect mainly attributed to their high fiber content.
Objective: The current study was hypothesized to investigate the beneficial effects of methanol extract from the aerial part of Plantago major (Pm) on hyperglycemia-mediated oxidative stress and inflammatory responses Alloxan induced diabetes mellitus, and in normal rats.
Materials and methods: Experimental diabetes was induced by intraperitoneal injection of 100 mg/kg body weight Alloxan. Normal and Diabetic rats were administered with distilled water, methanol extract of.. View More»
DOI:
10.4172/2167-0412.1000292