Medicinal & Aromatic Plants
Open Access

Bule MH

Publications

• Research Letter
  A Comparative Study of the Hypoglycemic Effect of Aqueous and Methanolic Extracts of Myrtus communis on Alloxan Induced Diabetic Siwis Albino Mice
  Author(s): Issa IA and Bule MHIssa IA and Bule MH
  
  Diabetes mellitus is metabolic syndrome that causes disability, early death, and many other complications like neuropathy, nephropathy, retinopathy, amputation, erectile dysfunction and cardiovascular disease. The study was designed to evaluate anti-diabetic activity and anti-toxicity of aqueous and methanolic extracts of M. communis. The extracts were chemically screened for phytochemicals. Anti-diabetic effect of aqueous and methanolic extracts of M. communis were separately evaluated by administering these extracts orally to alloxan induced diabetic mice at single dose of 500, 750 and 1000 mg/kg body weight. On the other hand, the antitoxicity studies of the aqueous extract of M. communis indicated that the extract is non-toxic and safe.The results indicate that mean lethal dose (LD50) for aqueous extract of M. communis was 8125 mg/kg. Aqueous extract of M. communis significantly l.. View More»
  DOI: 10.4172/2167-0412.1000190

  Abstract PDF

Relevant Topics