Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
+44 1300 500008
ISSN: 2167-0412
+44 1300 500008
Aliyu U
Kenya
Research Article
Antinociceptive Activities of Acetone Leaves Extracts of Carissa Spinarum
in Mice
Author(s): Mworia JK, Gitahi SM, Juma KK, Njagi JM, Mwangi BM, Aliyu U, Njoroge WA, Mwonjoria KJ, Mawia AM, Nyamai DW, Ngugi MP and Ngeranwa JJNMworia JK, Gitahi SM, Juma KK, Njagi JM, Mwangi BM, Aliyu U, Njoroge WA, Mwonjoria KJ, Mawia AM, Nyamai DW, Ngugi MP and Ngeranwa JJN
Despite the progress that has occurred in recent years in the development of therapies for pain, there is still a need for effective and potent analgesics for pain. Pain is defined as unpleasant feeling essential for body’s defense system. It acts as a warning signal against disturbances in the body. Conventional antinociceptives are expensive and have many side effects. Continued use of these drugs may lead to tolerance and resistance. Medicinal plants have been used to relieve pain and form a better alternative. Herbal antinociceptives are affordable and have arguably fewer side effects. Carissa spinarum (Linn) is used to treat rheumatoid pain, fever and inflammation related disorders. This plant is used locally by people in Embu County as analgesics. This study was designed to bioscreen the acetone leaves extracts C.spinarum (Linn) for anti-nociceptive potential. The plant pa.. View More»
DOI:
10.4172/2167-0412.S1-006