Journal of Nutrition & Food Sciences

Journal of Nutrition & Food Sciences
Open Access

ISSN: 2155-9600

Vijay Ganji

Qatar University, Doha, Qatar

  • Research Article   
    Pathogenetic Mechanisms of Metabolic Syndrome Development and its Correction with Grape-Derived Stilbene Concentrate
    Author(s): Vitalina Petrenko* and Vijay Ganji

    Aim: The aim of the research was to investigate the dynamics of the parameters of carbohydrate and lipid metabolism, markers of associated inflammation in an induced metabolic syndrome (MetS) model, and to estimate the effectiveness of its treatment using a grape-derived stilbene concentrate (GDSC). Methods: The research was performed on 40 white Wistar male rats of the SPF category aged 12 weeks. The MetS was induced using the fructose model (feeding the rats a diet with a 60% fructose content for 24 weeks). Rats with induced MetS were treated with GDSC, which was obtained by water-alcohol extraction of Vitis vinifera (Ressfood LLC, Russia). Results: Induction of the experimental MetS was accompanied by the development of abdominal obesity, hyperglycemia, increased lipids levels, cardiomyopathy and damage of blood ves.. View More»
    DOI: 10.35248/2155-9600.20.10.1000769

    Abstract HTML PDF