Mycobacterial Diseases
Open Access
ISSN: 2161-1068
+44 1478 350008
ISSN: 2161-1068
+44 1478 350008
Yoshitaka Yamazaki
Suzaka Hospital,
1332 Suzaka City, Nagano Prefecture 382-0091
Japan
Case Report
Fulminant Pulmonary Tuberculosis by Infliximab in Patient with
Rheumatoid Arthritis
Author(s): Mineyuki Hama, Yoshitaka Yamazaki, Makoto Kosaka, Atsuhito Ushiki, Norihito Goto, Mariko Sugawara and Masayuki HanaokaMineyuki Hama, Yoshitaka Yamazaki, Makoto Kosaka, Atsuhito Ushiki, Norihito Goto, Mariko Sugawara and Masayuki Hanaoka
A 72-year-old Japanese woman who had been suffering from rheumatoid arthritis for five years started treatment with infliximab. The screening of a chest X-ray before initiating infliximab treatment showed no abnormal shadows. After a month of infliximab, she was admitted to the emergency hospital with a half-month history of a fever, fatigue, dyspnea, and cough. She was diagnosed with tuberculosis from a culture smear and referred to our hospital. The chest images showed a bilateral massive cavity and infiltration. Despite the administration of an anti-tuberculous agent, the cavity and infiltration were enlarged on a chest X-ray and the patient died due to respiratory failure. Cases of tuberculosis resulting in death after a short duration of infliximab treatment have been rarely reported. We speculate that chest CT and the interferon-gamma release assay (IGRA) for tuberculosis screen.. View More»
DOI:
10.4172/2161-1068.1000206