Transcriptomics: Open Access
Open Access
ISSN: 2329-8936
ISSN: 2329-8936
Wenyan Wu
China
Research Article
Correlation of a Serological Proteome and Lung Cancer Prognosis
Author(s): Yongzhen Zhang, Wenyan Wu, Fang Su, Zhaohui Ma, Yi Xu, Yuan Wang, Ling Cao, Ruifeng Zhang, Xinchen Wang, Guodong Li, Jianzhong Ma and Christopher I AmosYongzhen Zhang, Wenyan Wu, Fang Su, Zhaohui Ma, Yi Xu, Yuan Wang, Ling Cao, Ruifeng Zhang, Xinchen Wang, Guodong Li, Jianzhong Ma and Christopher I Amos
Abstract Background To study the correlation of the lost goodwill target (LGT) proteome and the prognosis in patients with lung cancer and explore whether the LGT proteome can be used as an accurate and reliable prognostic biomarker for lung cancer. Methods One hundred eighty eight patients with lung cancer were enrolled in the Shanxi Cancer Hospital, China. For each patient, LGT test in serum was performed using the technique SELDITOF-MS after the pathological diagnosis. Kaplan- Meier survival analysis, Log-rank test and multivariate Cox proportional hazards regression analysis were performed to explore the influence of LGT different expression on the prognosis. Results The median survival times were 865 and 514 days in the LGT negative and LGT positive groups, respectively. There was statistically significant difference between the two survival curves, and the survival rate of the L.. View More»
DOI:
10.4172/2329-8936.1000103