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Table of Contents
About the Journal
Genetics encompasses study of structure and function of genes; causative factors, physiological consequences of genetic variations as well as various other aspects of heredity. Genetic studies involve in depth analysis of diverse features of DNA and chromosomes, reproduction and heredity, recombination and genetic linkage, gene expression, the central dogma of life, genetic mutations, evolution, genomics and DNA sequencing. Genetics helps in comprehending the molecular aspects of various diseases and helps us to formulate specific treatment and management strategies. Scientists are currently engaged in finding the cure for chronic diseases by modifying the associated genes, a process referred to as gene therapy and it is speculated as the future of medical treatment practices.
Genetic mutation is a permanent change in the DNA. Mutations may or may not produce changes in the organism. Hereditary mutations and Somatic mutations are the two types of Gene mutations. Former types are inherited from the parents and are present in every cell of the human body whereas latter type may occur at some point of life time due to environmental factors.
Certain enzymes repair gene mutations that could cause a genetic disorder. These enzymes identify and repair mistakes in DNA before the gene is expressed and an altered protein is produced. When a mutation alters a protein, it can disrupt normal development. Mutation may occur from a single DNA to a large segment of chromosome that involves multiple genes.
Nuclear medicine is a medical speciality that uses small amounts of radioactive material in the diagnosis and treatment of the disease in early stage like heart disease, neurological disorders and several types of cancer and other abnormalities of the body. Nuclear medicine procedures pinpoint the molecular activity within the body and they offer the potential to identify disease in its earliest stages as well as a patient’s immediate response to therapeutic interventions. It gives the medical information in a safe and painless manner that may otherwise be unavailable, requires surgery or more expensive and invasive diagnostic tests. A pharmaceutical is attached to a small quantity of radioisotopes and the combination is called radiopharmaceutical. There are different radiopharmaceuticals available for different parts of the body and their use depends on the condition to be diagnosed and treated.