Epigenetics Research: Open Access
Open Access

About the Journal

Epigenetics as a word itself means that addition to Genetic sequence. It encompasses any process that alters the activity of gene without alteration in DNA sequence and these modifications can be later transformed into the daughter cells, however, some exceptions are there as some epigenetic changes could be reversed. The epigenetics process includes methylation, phosphorylation, acetylation, sumoylation, and ubiquitylation. The epigenetic mechanisms normally occur as natural and essential phenomena in the body of living organisms, these changes help in switching the genes on and off. However, if they occur imperfectly it may result in many adverse health conditions. 

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Gene expression refers to the frequency with which proteins are made from the instructions in genes. While genetic changes can change which protein is produced, epigenetic changes affect gene expression to "turn on" and "turn off" genes. Because environment and behavior, such as diet and exercise, can cause epigenetic changes, it is easy to see the connection between your genes and your behavior and environment.

The epigenetics mechanism has links to various diseases, example the epigenetic mechanisms are one of the top five cancer considerations, accounting for one-third to one-half of known genetic changes. It makes sense to counteract these changes through epigenetic treatments. These changes seem to be an ideal target because, unlike mutations in the DNA sequence, they are inherently reversible. The most popular of these treatments aim to alter DNA methylation or histone acetylation.

Scope and Relevance of Epigenetics Research
Epigenetic modifications	Cancer epigenetics	Epigenetics in psychology	Epigenetic clinical trials
Chromatin remodelling	Neuroepigenetics	Developmental epigenetics	Epigenetics of aging
DNA methylation	Nutrigenomics	Epigenetic therapy	Plant epigenetics
Nucleosome modification	Cardiovascular epigenetics	Epigenetic disease model organisms	Epigenetic therapies
Gene silencing	Reproductive epigenetics	Environmental epigenetics	Epigenetic tools