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Table of Contents
About the Journal
Epigenetics as a word itself means that addition to Genetic sequence. It encompasses any process that alters the activity of gene without alteration in DNA sequence and these modifications can be later transformed into the daughter cells, however, some exceptions are there as some epigenetic changes could be reversed. The epigenetics process includes methylation, phosphorylation, acetylation, sumoylation, and ubiquitylation. The epigenetic mechanisms normally occur as natural and essential phenomena in the body of living organisms, these changes help in switching the genes on and off. However, if they occur imperfectly it may result in many adverse health conditions.
Submit manuscript at: https://www.longdom.org/submissions/epigenetics-research-open-access.html or send as an e-mail attachment to the Editorial Office [email protected]
Gene expression refers to the frequency with which proteins are made from the instructions in genes. While genetic changes can change which protein is produced, epigenetic changes affect gene expression to "turn on" and "turn off" genes. Because environment and behavior, such as diet and exercise, can cause epigenetic changes, it is easy to see the connection between your genes and your behavior and environment.
The epigenetics mechanism has links to various diseases, example the epigenetic mechanisms are one of the top five cancer considerations, accounting for one-third to one-half of known genetic changes. It makes sense to counteract these changes through epigenetic treatments. These changes seem to be an ideal target because, unlike mutations in the DNA sequence, they are inherently reversible. The most popular of these treatments aim to alter DNA methylation or histone acetylation.
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Scope and Relevance of Epigenetics Research |
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Epigenetic modifications |
Cancer epigenetics |
Epigenetics in psychology |
Epigenetic clinical trials |
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Chromatin remodelling |
Neuroepigenetics |
Developmental epigenetics |
Epigenetics of aging |
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DNA methylation |
Nutrigenomics |
Epigenetic therapy |
Plant epigenetics |
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Nucleosome modification |
Cardiovascular epigenetics |
Epigenetic disease model organisms |
Epigenetic therapies |
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Gene silencing |
Reproductive epigenetics |
Environmental epigenetics |
Epigenetic tools |