Mycobacterial Diseases
Open Access
ISSN: 2161-1068
+44 1478 350008
ISSN: 2161-1068
+44 1478 350008
Srinivas Rajagopala
St John’s Medical College Hospital,
Sarjapur Road, Bangalore, 560034
India
Case Report
Co-Infection with M. tuberculosis and M. leprae-Case Report and
Systematic Review
Author(s): Srinivas Rajagopala, Uma Devaraj, George D’Souza and Vijay V AithalSrinivas Rajagopala, Uma Devaraj, George D’Souza and Vijay V Aithal
Background: Co-infection with Mycobacterium tuberculosis and M. leprae is infrequent and conflicting views on their interaction exist.
Methods: We describe an immunocompetent male with simultaneously diagnosed primary multi-drug resistant extra-pulmonary tuberculosis and borderline lepromatous leprosy; we also review all cases of dual infection reported in English literature
Results: Our search yielded 156 cases of dual infections. Most dual infections were reported in middle-aged males. The sentinel infection was leprosy in 90.4%. Most affected patients had lepromatous leprosy (52.5%) but tuberculosis occurred throughout the disease spectrum of leprosy. The time to development of the second infection varied from 1 month-25 years (median 1.5 years). Tuberculosis was reported to occur in 2.5-13.5% of cases in six series.. View More»
DOI:
10.4172/2161-1068.1000118