Mycobacterial Diseases
Open Access
ISSN: 2161-1068
+44 1478 350008
ISSN: 2161-1068
+44 1478 350008
Rakesh Bhatnagar
Jawaharlal Nehru University
Others, BSL3 Laboratory, School of Biotechnology,
New Delhi-110067
India
Research Article
TBSURE: An Improved Multiplex Real-Time PCR for TB Detection and Differentiation from Nontuberculous Mycobacterial Diseases in Adult Indian Population
Author(s): Aakansha Bhawsar, Rajni Garg, Jasbeer Chhabra, Rajendra Prasad, Atul Thatai* and Rakesh Bhatnagar*Aakansha Bhawsar, Rajni Garg, Jasbeer Chhabra, Rajendra Prasad, Atul Thatai* and Rakesh Bhatnagar*
Background: Tuberculosis (TB), an infectious disease caused by bacterium Mycobacterium tuberculosis, has crossed the borders of developing nations and has now emerged as disease of global emergency due to an alarming increase in cases of co-infection with human immunodeficiency virus (HIV). Conventional diagnostics used for TB diagnosis like microscopy and culture although reliable are time consuming. Rapid diagnosis of the disease is required for early commencement of treatment of TB patients. The diagnosis of extra pulmonary tuberculosis (EPTB) is more troublesome due to limited accessibility of infection sites and lack of accurate differentiation from other granulomatous diseases. Currently, WHO advises use of Xpert MTB/RIF assay for EPTB diagnosis, but this assay cannot be used in resource constrained settings prevalent in most of parts of India.
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DOI:
10.4172/2161-1068.1000232