Mycobacterial Diseases
Open Access
ISSN: 2161-1068
+44 20 3868 9735
ISSN: 2161-1068
+44 20 3868 9735
Ondimu Thomas Orindi
Jaramogi Oginga Odinga University Nairobi,
Kenya
Research Article
Comparative Study of Smear Microscopy, Gene Xpert and Culture and Sensitivity Assays in Detection of Mycobacterium tuberculosis on Sputum Samples among Tuberculosis Suspected Cases in Nyamira County Referral Hospital
Author(s): Grace Moraa Orina, Samson Adoka Ong\'wen, Asito Stephen Amolo and Ondimu Thomas OrindiGrace Moraa Orina, Samson Adoka Ong\'wen, Asito Stephen Amolo and Ondimu Thomas Orindi
The laboratory diagnosis of pulmonary tuberculosis and smear-negative pulmonary tuberculosis in resourcelimited countries are often based on X-ray and sputum smear microscopy. These diagnostic tools require experts, have long turnaround time, and cannot detect resistance to Tuberculosis (TB) drugs and TB in individuals with Human immunodeficiency virus. Recently there was development of GeneXpert MTB/Rif assay that has a short turnaround time and can detect resistance to rifampicin among TB patients but its utility has not been evaluated in Kenya. This study investigated the comparative sensitivity and specificity of smear microscopy and culture relative to GeneXpert MTB/Rif assay among suspected TB patients. A cross-sectional study was conducted in Nyamira County Referral Hospital among suspected TB patients and both results recorded. Culture for Mycobacterium t.. Read More»
DOI:
10.4172/2161-1068.1000249
