Family Medicine & Medical Science Research
Open Access

Nissar A Darmani

Biography

Associate Dean for Basic Sciences and Research/Chair, Basic Medical Sciences, Professor of Pharmacology, Department of Basic Medical Sciences, Western University of Health Sciences. College of Osteopathic Medicine of the Pacific. Nissar Darmani was born in Kabul, Afghanistan. In 1971 he moved to England where he completed high school, undergraduate BSc in Pharmacology/Biochemistry, Leeds university) and postgraduate studies MSc in Applied Pharmacology and PhD in Neuropharmacology, UWIST, UK.

Research Interest

Dr. Darmani has several avenues of research interest that include:

Developmental effects of drugs of abuse on the newborn.

Serotonergic mechanisms of cocaine's actions.

Mode of action of antidepressant drugs.

Adaptive mechanisms of serotonergic 5-HT2 receptor functions.

The role of delta-9 -THC and synthetic cannabinoids on chemotherapy- and radiotherapy-induced vomiting. His laboratory had the first opportunity to demonstrate the mechanisms of antiemetic actions of marijuana.

Role of 5-HT3-, Dopamine D2/3-, Lekotriene CysLT1- and NK1- receptors in emesis and application of their antagonists as antiemetics.

Another of his research interests involves the role of osteopathic manipulative medicine on the blood levels of endogenous cannabinoid-like compounds and other pain markers in patients with back pain. He had been successful in obtaining several million dollars of research grants from numerous funding agencies including the Pharmaceutical industry, the National Institute of Drug Abuse, the National Institute of Cancer, the Department of Defense and the Environmental Protection Agency.

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