ISSN: 2161-1068
						Lydia Mosi
	
					    												
Scotland						                            
                            
						
 Review Article
												Genotyping Tools for Mycobacterium ulcerans Drawbacks and Future Prospects 						
Author(s): Charles A Narh, Lydia Mosi, Charles Quaye, Samuel CK Tay, Bassirou Bonfoh and Dziedzom K de Souza
Charles A Narh, Lydia Mosi, Charles Quaye, Samuel CK Tay, Bassirou Bonfoh and Dziedzom K de Souza
             
						
												
				 Mycobacterium ulcerans infection (Buruli ulcer) is a neglected but treatable skin disease endemic in over 30 countries. M. ulcerans is environmental mycobacteria with an elusive mode of transmission to humans. Ecological and Molecular epidemiological studies to identify reservoirs and transmission vectors are important for source tracking infections especially during outbreaks and elucidating transmission routes. Research efforts have therefore focused on genotyping strains of the mycobacteria from clinical and environmental samples. This review discusses genotyping tools for differentiating M. ulcerans strains from other environmental and Mycolactone Producing Mycobacteria (MPMs). We highlight tools that have been adapted from related fields and propose ways these could be enhanced to resolve intra-species variation for epidemiological, transmission, evolutionary studies, and detecti.. View More»
				  
												DOI:
												 10.4172/2161-1068.1000149