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John F Keaney

Biography

John F. Keaney, Jr., MD, is professor of medicine, chief of cardiovascular medicine, and medical director for the Heart and Vascular Center of Excellence at the University of Massachusetts Medical School and UMass Memorial Medical Center. A native of Massachusetts, Dr. Keaney graduated magna cum laude from Harvard College with a degree in biochemistry and molecular biology. He then received his MD degree cum laude from Yale University School of Medicine and returned to Massachusetts to train in internal medicine, cardiology, and interventional cardiology at Brigham and Women’s Hospital and Harvard Medical School. He started on the faculty at Brigham and Women’s Hospital, moving to Boston University School of Medicine in 1994 where he rose to the rank of professor of medicine in 2003 and subsequently became vice chairman (research) of the Department of Medicine. Dr. Keaney then joined the University of Massachusetts Medical School in 2007 as chief of cardiovascular medicine. In 1993, Dr. Keaney and his collaborator, Dr. Joseph Vita, discovered that the function of blood vessels depends on controlling oxidation-reduction reactions in the endothelial cells that line the blood vessel surface. Since this discovery, Dr. Keaney’s laboratory has defined how blood vessels resist injury from conditions such as high cholesterol, high blood pressure, and diabetes. His studies provided critical insight into why only certain patients develop heart attacks and how vascular disease can be treated and reversed. His work has been recognized by election to international honor societies for physician-scientists, such as the American Society for Clinical Investigation and the Association of University Cardiologists. He is also the cardiovascular editor for the New England Journal of Medicine, the #1-ranked medical journal in the world.

Research Interest

Coronary Artery Disease
Preventive Cardiology
Valvular Heart Disease

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