Mycobacterial Diseases
Open Access
ISSN: 2161-1068
ISSN: 2161-1068
Gerald Mboowa
School of Allied Health Sciences, International Health Sciences University,
P.O Box 7782, Kampala
Uganda
Review Article
Tuberculosis and Genetics of Sub-Saharan Africa Human Population
Author(s): Gerald MboowaGerald Mboowa
Sub-Saharan Africa has continued leading in the prevalence and incidence of tuberculosis (TB). The epidemiological triad of infectious diseases includes a susceptible host, pathogen/agent, and environment. Sub- Saharan Africa has the highest prevalence and incidence of TB. It is imperative that all aspects of vertices of the infectious disease triad are analysed to better understand why this is so. Many studies have been done to address this intriguing reality though these have mainly addressed pathogen and environmental components of the triad regarding TB infection. The host factors have not been exhaustively studied in this high TB burden region probably due to lack of the necessary expertise and technologies among African scholars yet three components of the triad interact to determine the disease outcome. Amongst host factors, genetic structure of the host greatly affects progres.. View More»
DOI:
10.4172/2161-1068.1000164