Advances in dairy Research

Advances in dairy Research
Open Access

ISSN: 2329-888X

+44 1300 500008

Fueldner C

Fueldner C

Germany

Publications
  • Research Article
    Discovery and Validation of Immunological Biomarkers in Milk for Health Monitoring of Dairy Cows - Results from a Multiomics Approach
    Author(s): Zoldan K, Schneider J, Moellmer T, Fueldner C, Knauer J, Fuerll M, Starke A, Specht M, Reiche K, Hackermueller J, Kalkhof S, von Bergen M, Bergfeld U, Fischer R, Pache S, Joerg Lehmann Zoldan K, Schneider J, Moellmer T, Fueldner C, Knauer J, Fuerll M, Starke A, Specht M, Reiche K, Hackermueller J, Kalkhof S, von Bergen M, Bergfeld U, Fischer R, Pache S, Joerg Lehmann

    At onset of milk production and in early lactation highly producing dairy cows are most susceptible for inflammatory diseases due to functional suppression of immune cells. Intensive supervision of the animals is essential and implementation of new technologies to on-farm routines will be the next step to provide automation and improvement of herd health monitoring programs. Objective of our study was to identify and validate immunological biomarkers in milk that indicate extra-mammary inflammatory diseases to characterize the general health status of highly-producing dairy cows. In total 89 healthy and 75 diseased animals (German Holstein cows) were included. Diseases were distinguished by either systemic (extra-mammary) occurrence or those affecting the mammary gland (mastitis) and further classified by their severity. For protein biomarker discovery we used a top-down app.. View More»
    DOI: 10.4172/2329-888X.1000182

    Abstract PDF

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