Journal of Nutrition & Food Sciences

Journal of Nutrition & Food Sciences
Open Access

ISSN: 2155-9600

Yvonne Mödinger

BioTeSys GmbH, Schelztorstraße 54-56, 73728 Esslingen, Baden-Württemberg, Germany

  • Research Article   
    LDL-cholesterol lowering effect of hydroxytyrosol (HTEssence®): A randomized double-blind, placebo-controlled parallel study
    Author(s): Katharina Knaub*, Yvonne Mödinger, Manfred Wilhelm and Christiane Schön

    Background: Nutraceuticals containing hydroxytyrosol have been shown to exert a wide range of beneficial effects on the cardiovascular system like lipid modification and cholesterol reduction. The aim of this randomized doubleblind, placebo-controlled parallel study was to investigate the effects of a pure, synthetic form of hydroxytyrosol (HTEssence®) on the lipid profile in subjects with elevated LDL-cholesterol level. Methods: 92 subjects underwent a 12-week intervention with hydroxytyrosol or placebo. At baseline, after 6 and 12 weeks of intervention the lipid profile of the subjects was assessed.The study was conducted in accordance with the guidelines for Good Clinical Practice (GCP) andwas registered in the German Clinical Trials Register (DRKS00015251). Results: A significant delta change of .. View More»
    DOI: 10.35248/2155-9600.20.10.1000778

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