Journal of Nutrition & Food Sciences
Open Access
ISSN: 2155-9600
ISSN: 2155-9600
Ulm University of Applied Sciences, Department of Mathematics, Natural and Economic Sciences, Albert-Einstein-Allee 55, 89081 Ulm, Baden-Württemberg, Germany
Research Article
LDL-cholesterol lowering effect of hydroxytyrosol (HTEssence®): A randomized double-blind, placebo-controlled parallel study
Author(s): Katharina Knaub*, Yvonne Mödinger, Manfred Wilhelm and Christiane Schön
Background: Nutraceuticals containing hydroxytyrosol have been shown to exert a wide range of beneficial effects on the cardiovascular system like lipid modification and cholesterol reduction. The aim of this randomized doubleblind, placebo-controlled parallel study was to investigate the effects of a pure, synthetic form of hydroxytyrosol (HTEssence®) on the lipid profile in subjects with elevated LDL-cholesterol level.
Methods: 92 subjects underwent a 12-week intervention with hydroxytyrosol or placebo. At baseline, after 6 and 12 weeks of intervention the lipid profile of the subjects was assessed.The study was conducted in accordance with the guidelines for Good Clinical Practice (GCP) andwas registered in the German Clinical Trials Register (DRKS00015251).
Results: A significant delta change of .. View More»
DOI:
10.35248/2155-9600.20.10.1000778