Translational Medicine
Open Access

Tanmoy Bhowmik

Publications

• Research Article
  Gecko Skin Extract Induce Cytotoxicity and Apoptosis in Human Breast Cancer Cell Line
  Author(s): Tanmoy Bhowmik, Dilip Muhuri, Ajay Kumar Biswas, Aparna Gomes and Antony Gomes* Tanmoy Bhowmik, Dilip Muhuri, Ajay Kumar Biswas, Aparna Gomes and Antony Gomes*
  
  Gecko has been used against malignant tumors in medicinal practice in china, especially digestive system tumors such as esophageal cancer, gastric cancer, and liver cancer. Reduce inflammation, active against allergic responses, swelling having low toxicity are other activity of Gecko skin extract, has been mentioned in chinese folk medicine. The aim of this study was to examine the alcoholic skin extract of Gecko species induced cytotoxicity and apoptosis activity in breast cancer (MCF7) cell line. in vitro, the inhibitory effect of gecko skin alcohol extract (GSAE) on cytotoxicity of human breast cancer cells was measured by MTT assay and trypan blue exclusion assay which resulted in MCF7 cell proliferation was significantly inhibited in both dose- and time- dependent manner (P < 0.01). High percentage (71.19%) early cell apoptosis in GSAE-treated group (IC50 dose) exhibited sele.. View More»
  DOI: 10.4172/2161-1025.1000158

  Abstract PDF

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