Translational Medicine
Open Access

Sourav Ghosh

Publications

• Research Article
  Antiscorpion Venom Activity of an Aromatic Compound having Carbohydrate Moiety Isolated from Hemidesmus indicus (Anantamul) Root Extract in Experimental Animal Models
  Author(s): Antony Gomes*, Rinku Das, Sourav GhoshAntony Gomes*, Rinku Das, Sourav Ghosh
  
  The present study established the anti scorpion venom activity of an aromatic compound purified from the Indian medicinal plant Hemidesmus indicus (anantamul) root extract in experimental animals. The compound (H.I-1) was isolated by silica gel column chromatography and thin layer chromatography and spectral analysis was done by IR and H1 NMR. Animal ethical clearance was obtained before experiment. Anti scorpion venom activity was evaluated using various in vivo tests, urine qualitative analysis, renal toxicity markers (urea and creatinine), hepatotoxicity markers (AST and ALT), myotoxic markers (LDH and CPK) and oxidative stress markers (LPO, GPX and GSH) in animal models. Statistical analysis was done by one way ANOVA, values expressed as mean±SEM, P<0.05 was considered as statistically significant. Silica gel column chromatography I & II produced an active compound (H... View More»
  DOI: 10.4172/2161-1025.1000191

  Abstract PDF

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