Translational Medicine

Translational Medicine
Open Access

ISSN: 2161-1025

Satheesh S Gottipati

  • Review Article
    A Concise Review on Extensive use of Proton Pump Inhibitors
    Author(s): Manukonda Ajay, Ramesh G, Satheesh S Gottipati and Srinivasa Babu PManukonda Ajay, Ramesh G, Satheesh S Gottipati and Srinivasa Babu P

    Proton Pump inhibitors have been a landmark since their inception through their safe and efficacious use in inhibition of acid secretion. They superseded another class of drugs that serve the same purpose but with a different mode of action termed “H2 receptor antagonists”. PPI’s (Proton pump inhibitors) prescribing has been dramatically increased over the years owing to their role in treating acid related disorders like GERD (Gastro Esophageal Reflux Disease), Gastric and Duodenal Ulcers, NSAID (Non-Steroidal Anti Inflammatory Drugs) induced ulcers etc. They are available as over the counter medications in many countries. But, the long-term use of PPi’s (Proton pump inhibitors) have certain limitations that has been extensively studied. Deprescribing has been suggested to reduce polypharmacy where the PPi (Proton pump inhibitors) use may be inappropriate or wi.. Read More»
    DOI: 10.4172/2161-1025.1000204

    Abstract PDF

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