Journal of Nutrition & Food Sciences
Open Access
ISSN: 2155-9600
ISSN: 2155-9600
Richard J Bloomer
Center for Nutraceutical and Dietary Supplement Research, School of Health Studies,
Memphis, TN 38152
Tanzania
Research Article
Blood MSM Concentrations Following Escalating Dosages Of Oral MSM In Men And Women
Author(s): Richard J Bloomer, Matthew Butawan, Ling Lin, Dejian Ma and Charles R YatesRichard J Bloomer, Matthew Butawan, Ling Lin, Dejian Ma and Charles R Yates
Background: Methylsulfonylmethane (MSM) is an organosulfur compound used as a dietary supplement. We determined the plasma MSM concentration following four months of oral MSM supplementation at escalating dosages.
Methods: 45 men and women (25 ± 5 years) participated in this study. Subjects were assigned to ingest either 1, 2, or 3 grams of MSM daily for 16 weeks. Blood was collected at baseline and following weeks 4, 8, 12, and 16 and analyzed for plasma MSM concentration using a LC-MS/MS method.
Results: A group (p<0.0001), time (p<0.0001), and group x time (p=0.0005) interaction was noted. Values were higher for the 2 and 3 grams/day group as compared to the 1 gram/day group and were also higher for the 3 grams/day group as compared to the 2 grams/day group (p<0.05). Values at weeks 4, 8, 12, and.. View More»
DOI:
10.4172/2155-9600.1000748