Journal of Nutrition & Food Sciences
Open Access
ISSN: 2155-9600
ISSN: 2155-9600
Matthew Butawan
Tanzania
Research Article
Blood MSM Concentrations Following Escalating Dosages Of Oral MSM In Men And Women
Author(s): Richard J Bloomer, Matthew Butawan, Ling Lin, Dejian Ma and Charles R YatesRichard J Bloomer, Matthew Butawan, Ling Lin, Dejian Ma and Charles R Yates
Background: Methylsulfonylmethane (MSM) is an organosulfur compound used as a dietary supplement. We determined the plasma MSM concentration following four months of oral MSM supplementation at escalating dosages.
Methods: 45 men and women (25 ± 5 years) participated in this study. Subjects were assigned to ingest either 1, 2, or 3 grams of MSM daily for 16 weeks. Blood was collected at baseline and following weeks 4, 8, 12, and 16 and analyzed for plasma MSM concentration using a LC-MS/MS method.
Results: A group (p<0.0001), time (p<0.0001), and group x time (p=0.0005) interaction was noted. Values were higher for the 2 and 3 grams/day group as compared to the 1 gram/day group and were also higher for the 3 grams/day group as compared to the 2 grams/day group (p<0.05). Values at weeks 4, 8, 12, and.. View More»
DOI:
10.4172/2155-9600.1000748