Translational Medicine
Open Access

Lijuan Zhang

Publications

• Research Article
  Tumor-Dependent and -Independent Serum/Plasma Biomarkers for Early Diagnosis of Lung Cancer
  Author(s): Alexander Lu and Lijuan ZhangAlexander Lu and Lijuan Zhang
  
  Lung cancer continually leads in mortality among cancer patients in the world. In order to reduce the lung cancer mortalities, early treatment is required but early diagnosis is still farfetched because the hopeful serum/plasma biomarkers identified so far lack sufficient sensitivity, specificity, and reproducibility even for diagnosis of lung cancer at late stage. During the past decades, the realization that the genetic mutations are not the only blame and the abnormal lung tissue instigated by aging, cigarette smoking, and environmental toxins plant the “soil” for lung cancer. Such discovery leads to the successful development of novel anti-cancer drugs that target the “soil” by either inhibiting angiogenesis process required for cancer cells to expand or by empowering the immune cells to kill the cancer cells in tumor. Based on .. View More»
  DOI: 10.4172/2161-1025.1000160

  Abstract PDF

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