Journal of Genetic Syndromes & Gene Therapy
Open Access
ISSN: ISSN: 2157-7412
+44 1223 790975
ISSN: ISSN: 2157-7412
+44 1223 790975
Kenneth Blum
Mcknight Brain Institute,
College of Medicine Gainesville, Florida
Tanzania
Review Article
Neuro-Genetics of Reward Deficiency Syndrome (Rds) as the Root Cause of
Author(s): Kenneth Blum, John Bailey, Anthony M Gonzalez, Marlene Oscar-Berman, Yijun Liu, John Giordano, Eric Braverman and Mark GoldKenneth Blum, John Bailey, Anthony M Gonzalez, Marlene Oscar-Berman, Yijun Liu, John Giordano, Eric Braverman and Mark Gold
Now after many years of successful Bariatric (weight-loss) surgeries directed at the obesity epidemic clinicians are reporting that some patients are replacing compulsive overeating with newly acquired compulsive disorders such as alcoholism, gambling, drugs and other addictions like compulsive shopping and exercise. This review article explores evidence from psychiatric genetic animal and human studies that link compulsive overeating and other compulsive disorders to explain the phenomenon of addiction transfer. Possibly due to neurochemical similarities overeating and obesity may act as protective factors reducing drug reward, and addictive behaviors. In animal models of addiction withdrawal from sugar induces imbalances in the neurotransmitters, acetylcholine and dopamine, similar to opiate withdrawal. Many human neuroimaging studies have supported the concept of linking food craving .. View More»
DOI:
10.4172/2157-7412.S2-001