Gene targeting is a genetic technique that uses homologous recombination to change an endogenous gene. It can be used to delete a gene, add a gene and introduce point mutations. Gene targeting can be permanent or conditional. Gene targeting has been widely used to study human genetic diseases by removing ("knocking out"), or adding ("knocking in"), specific mutations of interest to a variety of models.
Related Journals of Gene Targeting
Cloning & Transgenesis, Journal of Proteomics & Bioinformatics, Hereditary Genetics: Current Research, Translational Medicine, Human Genetics & Embryology, American Journal of Medical Genetics - Seminars in Medical Genetics, American Journal of Medical Genetics, Neuropsychiatric Genetics, Angiogenesis, Animal Genetics.