Journal of Nutrition & Food Sciences
Open Access
ISSN: 2155-9600
ISSN: 2155-9600
Hassan A. Abdel-Rahman
Saudi Arabia
Research Article
Synergistic Effect of Thymus vulgaris Essential Oil Oral Administration on Topically Treated Wound with Chitosan, Thyme Essential Oil and their Combination in Rats
Author(s): Hassan Barakat, Hamad S. Aljabeili and Hassan A. Abdel-RahmanHassan Barakat, Hamad S. Aljabeili and Hassan A. Abdel-Rahman
Herbal medication from natural resources plays an important role as antioxidant, antibacterial agent and demonstrating an inimitable property in wound curative rather than synthesized-toxic materials. The present investigation was designed to evaluate the potential healing efficacy of thyme (Thymus vulgaris) essential oil (TEO) oral adminstartion on topically treated wound with chitosan, TEO and their combination in vitro. Practically, effect of TEO oral administration on topically treated wounded rats in comparing to topical application of betadine for two weeks was carried out. Remarkably, treated group with TEO topically and orally exhibited the highest wound contractions among all treated groups. In Parallel, histopathological alteration was improved in TEO topically and orally applications whereas no degeneration, necrosis & inflammatory cells infiltration i.. View More»
DOI:
10.4172/2155-9600.1000695