Journal of Nutrition & Food Sciences
Open Access
ISSN: 2155-9600
ISSN: 2155-9600
Cristina R
Italy
Research Article
Impaired Fat Oxidation and Reduced Resting Energy Expenditure after a Fat Load in Individuals with Liver Steatosis
Author(s): Samantha M, Elisa M, Daniele DB, Francesco P, Cristina R and Yvelise FSamantha M, Elisa M, Daniele DB, Francesco P, Cristina R and Yvelise F
To date, the factors involved in the progression from simple liver steatosis to liver fibrosis have not been clarified. The postprandial phase after a high fat meal is pro-inflammatory and chronic low-grade inflammation is associated with the development of non-alcoholic fatty liver disease. The purpose of this study was to evaluate the effect of an oral fat load on fat oxidation in individuals with vs. without liver steatosis. Twelve adults without liver steatosis and seventeen with liver steatosis underwent an oral tolerance tests with 190 grams of a fresh cream (343 kcal/100 g, calories from fats 84%). Respiratory quotient and resting energy expenditure were evaluated using indirect calorimetry at 0, 90 and 120 minutes after load ingestion. In the subjects without liver steatosis, the fat load induced a reduction in the respiratory quotient (basal value=0.88 ± 0.07 .. View More»
DOI:
10.4172/2155-9600.1000665