Derya Cicek Polat,S Sibel Gurpinar, Müjde Eryilmaz andMaksut Coskun
Ankara University, Turkey
Scientific Tracks Abstracts: J Nutr Food Sci
Epimedium L. (Berberidaceae) is a genus of approximately 52 taxa. A large part of this genus is endemic and found in the southwestern part of China. More than 15 species in this genus have a long history of use in traditional Chinese medicine (TCM). Epimedium spp. has been used to treat sexual dysfunction, prospermia, hyperdiuresis, osteoporosis, menopause syndrome, rheumatic arthritis, hypertension, and cardiovascular disease. Epimedium species are known as ‚??KeŇ?iŇ?k√ľlahńĪ‚?Ě ve ‚??Tekeotu‚?Ě in Turkey and two species are growing naturally in Turkey [E. pubigerum (DC.) Moren and Decaisne, E. pinnatum Fischer in DC subsp. colchicum (Boiss.) Busch]. The purpose of this study was to investigate the antimicrobial activity of aqueous, ethanolic and methanolic extracts of Epimedium species against some bacteria and yeast. Aqueous, ethanolic and methanolic extracts of Epimedium species were screened for their potential in vitro antibacterial activities against Staphylococcus aureus ATCC 25923, S. aureus ATCC 43300 (methicillin-resistant S. aureus), Enterococcus faecalis ATCC 29212, Bacillus subtilis ATCC 6633, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae RSKK 574 and antifungal activities against Candida albicans ATCC 10231. Ampicillin, ciprofloxacin and fluconazole were used as control. Experiments were repeated twice. According to obtained results from disc diffusion method, none of the extracts of Epimedium species showed antimicrobial activity against Gram negative test bacteria. Especially, methanol extracts have been shown to be effective on other microorganisms.
Derya Cicek Polat has completed her PhD, in April 2018. She is working as a Research Assistant at Ankara University, Faculty of Pharmacy in the Department of Pharmaceutical Botany.
E-mail: [email protected]