Discovery and Validation of Immunological Biomarkers in Milk for Health Monitoring of Dairy Cows - Results from a Multiomics Approach

Zoldan K¹, Schneider J¹, Moellmer T², Fueldner C¹, Knauer J¹, Fuerll M³, Starke A⁴, Specht M⁵, Reiche K^5,6, Hackermueller J^5,6,7, Kalkhof S^1,8,9, Von Bergen M⁸, Bergfeld U², Fischer R², Pache S² and Jorg Lehmann^1*

¹Fraunhofer Institute for Cell Therapy and Immunology, Department of Therapy Validation, Perlickstr. 1, 04103 Leipzig, Germany

²Saxon State Office for Environment, Agriculture and Geology, Am Park 3, 04886 Köllitsch, Germany

³Large Animal Clinic for Internal Medicine, University of Leipzig, Faculty of Veterinary Medicine, An den Tierkliniken 11, 04103 Leipzig, Germany

⁴Clinic for Ruminants and Swine, University of Leipzig, Faculty of Veterinary Medicine, An den Tierkliniken 11, 04103 Leipzig, Germany

⁵Fraunhofer Institute for Cell Therapy and Immunology, RNomics Unit, Perlickstr. 1, Leipzig, Germany

⁶Interdisciplinary Center for Bioinformatics and Bioinformatics Group, Department of Computer Science, University of Leipzig, Haertelstr, 16-18, Leipzig, Germany

⁷Helmholtz Centre for Environmental Research-UFZ, Young Investigators Group Bioinformatics and Transcriptomics, Department of Proteomics, Permoserstr, 15, Leipzig, Germany

⁸Department of Proteomics, Helmholtz Centre for Environmental Research-UFZ, Permoserstr, 15, 04318 Leipzig, Germany

⁹Department of Bioanalytics, University of Applied Sciences and Arts of Coburg, Friedrich-Streib-Str, 2, 96450 Coburg, Germany

^*Corresponding Author: Jorg Lehmann, Ph.D, Department of Therapy Validation, Fraunhofer Institute for Cell Therapy and Immunology, Perlickstr, 1, 04103 Leipzig, Germany, Tel: +49-341 / 35536 1205, Fax: +49-341/35536-8-1205 Email: