Journal of Nutrition & Food Sciences
Open Access
ISSN: 2155-9600
ISSN: 2155-9600
Department of Respiratory Medicine, Anhui Chest Hospital, China
Research Article
Effects of Nutritional Status on Peripheral Immune Cells in Patients with Nonsmall
Cell Lung Cancer
Author(s): Fang He, Dongliang Yang, Xiankui Zha, Ping Wang and Liang Xuan*
Background: The nutritional status affects gene expression in peripheral T lymphocytes; nevertheless, the link
between nutritional status and immunity of cancer patients is unclear. The aim of the research was to evaluate the
connection with nutritional parameters and the frequencies of T cells subsets on peripheral blood in non-small cell
lung cancer (NSCLC) patients.
Methods: We enrolled 170 NSCLC patients and 53 healthy volunteers who were age and gender matched. The
frequencies of circulating CD3+, CD4+, CD8+, naïve CD4+, memory CD4+, naïve CD8+, memory CD8+, and
regulatory T lymphocytes were assessed by the way of flow cytometry. Nutritional parameters including albumin,
globulin, albumin to globulin ratio (AGR), total protein (TP), pre-albumin (PA), body mass index (BMI), and
prognostic nutritional index (P.. View More»
DOI:
10.35248/2155-9600.22.12.1000856