Journal of Proteomics & Bioinformatics
Open Access
ISSN: 0974-276X
ISSN: 0974-276X
SK Jain
Jamia Hamdard, New Delhi: 110062
India
Research Article
Oxidative Stress and Histopathological Evaluation of Rat Lung Tissue
during Hypobaric Hypoxia
Author(s): Kumari Smita, MA Qadar Pasha and SK JainKumari Smita, MA Qadar Pasha and SK Jain
Hypobaric hypoxia (HH) is a condition associated with low partial pressure of oxygen in the atmosphere. This lowering of oxygen content in atmosphere leads to decreased circulating oxygen in the humans residing in these regions. This lowering of oxygen does not cause any serious complications in residents due to adaptation. On the other hand these extreme environments are challenging for high altitude (HA) sojourners as they develop range of illness from i.e. from mild altitude sickness to fatal diseases. Several studies have been carried on altitude environment to focus physiological complications and adaptation. Serum-based clinical studies are comparatively easy due to availability of human volunteers. Tissue-based studies are still challenging as the development of animal model is the only approach. Herein we report lung tissue based oxidative stress markers level in conjunction w.. View More»
DOI:
10.4172/jpb.1000358