The Human Proteome Project (HPP) is an international project initiated by the Human Proteome Organization (HUPO). Emergence of new techniques such as mass-spectrometry and Electrospray ionization the proteome of human can be determined to enhance the understanding the biology at cellular level. The chromosome-based HPP goals to develop our understanding of the human proteome with a focus on expanding the understanding of each and every gene on each chromosome. The biology/disease-based HPP aims to expand our understanding of the human proteome with a focus on important biology research aspects and ongoing disease-focused research. The Human Genome Project led to the finding that the protein coding genes are far less than the proteins that are found in humans. This diversity in the protein is due to alternative splicing and the post-translational modifications of the proteins. Thus the proteins are very good biomarkers for different diseases.
Related Journals of Human Proteome Project Applications
Journal of Data Mining in Genomics & Proteomics, Transcriptomics: Open Access, Journal of Molecular and Genetic Medicine, Molecular and Cellular Proteomics, International Journal of Proteomics, Journal of Proteomics and Genomics, Proteomics Insights, Proteomics, Bioinformatics & Genomics, Briefings in Functional Genomics, Human Genomics and Proteomics, Genomics Insights, BMC Systems Biology, Journal of Proteomics and Genomics