Journal of Proteomics & Bioinformatics
Open Access
ISSN: 0974-276X
ISSN: 0974-276X
Sarika
Scientist Statistics and Computer Application Unit,
Indian Institute of Pulses Research (ICAR), Kanpur 208024, Uttar Pradesh
India
Research Article
Prediction of MHC Binding Peptides and Epitopes from Coat Protein of Mungbean Yellow Mosaic India Virus-Ub05
Author(s): Sarika, Mohd. Akram, M. A. Iquebal and Naimuddin KSarika, Mohd. Akram, M. A. Iquebal and Naimuddin K
Mungbean yellow mosaic India virus (MYMIV) is recognized as one of the most economically important viruses that affects several leguminous crops like mungbean, urdbean, cowpea, pigeonpea etc. and occurs in Indian subcontinent. In the present study, coat protein of MYMIV is being used to fi nd out highly suitable MHC binding peptides and epitopes. Thirty nine peptide regions were found to have high af fi nity to TAP binding peptides using cascade support vector machine (SVM). Few of these coat protein TAP transporters are 201- NRFFKVNNY with score 9.208, 108- KRFCIKSVY with score 8.817, 44-RWTNRPMWR with score 8.790, 134- NTVMFKLCR with score 8.672 and 41- KRRRWTNRP with score 8.498 where the scores are based on the average af fi nity of an amino acid at particular position. The SVM based method for prediction of p.. View More»
DOI:
10.4172/jpb.1000136