ISSN: 0974-276X
Ross Holmes
Department of Urology
University of Alabama at Birmingham
Birmingham, USA
Ross Holmes studied calcium handling in a slime mold that was a multinucleated giant cell for his PhD studies in Biochemistry at the Australian National University, graduating in 1978. On moving to the University of Illinois at Champaign-Urbana he investigated the role of calcium and membrane perturbations in heart disease. Subsequently on joining the faculty at Wake Forest University in 1987 his focus shifted to examining calcium and oxalate handling associated with calcium oxalate stone disease. Major achievements while there were in establishing the role of dietary oxalate in stone disease, cloning the gene causing the rare disease, Primary Hyperoxaluria Type 2, identifying mutations in patients, and in clarifying the biochemical pathways associated with hepatic oxalate synthesis.
Biochemistry and Structural Biology