Journal of Proteomics & Bioinformatics
Open Access

Richard D. Smith

Biography

Dr. Smith's research interests span development of advanced analytical methods and instrumentation, with particular emphasis on high-resolution separations and mass spectrometry, and their applications in biological and biomedical research. Over the last 20 years, much of Dr. Smith's research has centered on creating and applying new ultra-sensitive technologies to quantitatively probe entire proteomes expressed by cells, tissues, and organisms. In the last decade, these efforts have broadened to include development and application of highly sensitive, high-throughput technologies for measuring the "pan-ome" (the array of biomolecule measurements that include the proteome, metabolome, lipidome, and glycome) to augment biological research. To enable much more effective pan-omics applications, he has recently been leading the development of novel Structures for Lossless Ion Manipulations (SLIM) and their use for very-high-throughput sample processing, reactions, separations, and other manipulations of ions in the gas phase, and particularly in conjunction with mass spectrometry.   Dr. Smith also is Director of Proteome Research at PNNL, Director of the NIH Research Resource for Integrative Biology, an adjunct faculty member in the chemistry departments at Washington State University and the University of Utah, and an affiliate faculty member in the Department of Chemistry at the University of Idaho and the Department of Molecular Microbiology & Immunology at Oregon Health & Science University. Dr. Smith completed his Ph.D. work in Physical Chemistry at the University of Utah.   Dr. Smith is the author/co-author of more than 1000 peer-reviewed journal articles and is the recipient of 55 patents and 10 R&D 100 Awards.

Research Interest

 Systems Biology, Biochemistry, Analytiacal methods, Bioinformatics, Proteomics

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