Journal of Proteomics & Bioinformatics

Journal of Proteomics & Bioinformatics
Open Access

ISSN: 0974-276X

+44 1223 790975

Ranjith N. Kumavath

Ranjith N. Kumavath
School of Biological Sciences, Central University of Kerala, Riverside Transit Campus,
Padanakkad (P.O) Kasaragod-671314, Kerala

  • Research Article
    Comparative Network Analysis of Two-Component Signal Transducing Protein-Protein Interactions in Enterococcus faecalis Sp.
    Author(s): Ranjith N. Kumavath and Pratap DRanjith N. Kumavath and Pratap D

    Background: Protein-Protein interactions network analysis of Enterococcus faecalis sp. in a comparative approach helps for the dissection of gene function, potential signal transduction, and virulence  pathways. Our research shed light on the comparative network analysis of two component signal transducing protein-protein interactions in ten different Enterococcus faecalis strains on the base of protein interactions prediction analysis and Host-Pathogen Interactions analysis using STRING and HPIDB databases. Around 30-40 proteins participate in the Two Component System of Enterococcus faecalis. Results: The network parameters of protein-protein interactions were calculated. The topological coefficient of almost all the strains of Enterococcus faecalis network perfectly followed a power law distribution (correlation) 1.000; R-squared) 1.00.. View More»
    DOI: 10.4172/jpb.1000249

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