ISSN: 2329-8901
+44 1223 790975
Peter Gal
Cone Health, 801 Green Valley Road, Greensboro, NC
Tanzania
Research Article
Effect of Routine Lactobacillus reuteri DSM 17938 use on Rates of Late-onset infection in Extremely-low-birth-weight Infants
Author(s): Peter Gal, Mary Ann VT Dimaguila, Tiffany Wilson and John E WimmerPeter Gal, Mary Ann VT Dimaguila, Tiffany Wilson and John E Wimmer
Background: Preterm infants are at high risk for late-onset infections due to gram-negative or fungal organisms. Evidence supports that a common source for these organisms may be the gastrointestinal tract. One theoretical way to change the infection rate is to alter the bacterial flora inhabiting the newborn gastrointestinal tract using probiotics. This study examines the impact of routine use of a probiotic, Lactobacillus reuteri DSM 17938 (BioGaia®), on the rate of late-onset gram-negative and fungal infection in neonates with birth weight ≤ 1000 grams. Methods: This is a retrospective cohort study comparing the rates of gram-negative bacterial and fungal infections in neonates with birth weight ≤ 1000 grams. The groups are separated into those neonates born from January 2004 to June 30, 2009, before introduction of L. r.. View More»
DOI:
10.4172/2329-8901.1000105