Journal of Proteomics & Bioinformatics
Open Access
ISSN: 0974-276X
ISSN: 0974-276X
Norbert Nwankwo
The Bio-Health Unit of the Centre for Computational Intelligence,
Leicester
Research Article
Digital Signal Processing Techniques:Calculating Biological Functionalities
Author(s): Norbert Nwankwo and Huseyin SekerNorbert Nwankwo and Huseyin Seker
Calculating Biological functionalities of proteins and presenting them numerically is an approach that will benefit the designing of drugs and vaccines. For example, potency of vaccines is known to be measured in terms of specificity, which is determined by bio-recognition (affinity), and sensitivity. Calculating the bio-recognition of peptides employed in the design of vaccines by means of procedures like the Digital Signal Processing (DSP) techniques rather than clinical experimentations not only gives room for the manipulation of the amino acids sequences of the peptides but also helps determine the degree of specificity of the antibody generated, hence the potency of the vaccine produced. This also provides opportunity for optimatization of the peptides for the desired biological characteristics. Also comparing the potency of peptide-based drugs through calculation of their biolog.. View More»
DOI:
10.4172/jpb.1000199