Journal of Proteomics & Bioinformatics
Open Access
ISSN: 0974-276X
+44 1223 790975
ISSN: 0974-276X
+44 1223 790975
Mohamed Saiel Saeed Alhamdani
Deutsches Krebsforschungszentrum (DKFZ),
Im Neuenheimer Feld 580, D-69120 Heidelberg
Germany
Review Article
Protein Microarrays as Tools for Functional Proteomics: Achievements, Promises and Challenges
Author(s): Smiths S Lueong, Jörg D Hoheisel and Mohamed Saiel Saeed AlhamdaniSmiths S Lueong, Jörg D Hoheisel and Mohamed Saiel Saeed Alhamdani
The quest for a better understanding of organisms, and the human body in particular, at a comprehensive level has stimulated the development of techniques and processes that permit the analysis and assessment of biomedical information at high throughput. This has had substantial impact, not only by merely gathering knowledge but also by making scientists aware of the necessity to view organisms as complex biological systems rather than an assembly of individual biochemical pathways. Proteomics is still lagging behind genomics in this holistic analysis, however, because of the much higher degree of complexity that needs to be dealt with. Protein arrays, among other techniques, offer the prospect of advancing global protein analysis, similar to the impact of arrays in genomics. In basic research, protein arrays already contributed substantially, permitting the identification of many pro.. View More»
DOI:
10.4172/jpb.S7-004