Journal of Proteomics & Bioinformatics
Open Access
ISSN: 0974-276X
ISSN: 0974-276X
Madhvi Shakya
India
Research Article
In silico Analysis and Homology Modelling of Antioxidant Proteins of Spinach
Author(s): Archna Sahay and Madhvi ShakyaArchna Sahay and Madhvi Shakya
Spinach is an important dietary vegetable often associated with bene fi cial health effects. In this paper, a bioinformatics and molecular modeling approach was adopted to explore properties and structure of spinach antioxidant proteins. The antioxidant proteins selected for this study are ascorbate peroxidase (APX), dehydro ascorbate reductase (DHAR), phospholipid hydroperoxide glutathione peroxidase-like protein (PHGPX) and 2-Cys peroxiredoxin BAS1 (2-CPs). Physico-chemical characterization interprets properties such as pI, EC, AI, GRAVY and instability index and provides data about these proteins and their properties. Prediction of motifs, patterns, disul fi de bridges and secondary structure were performed for functional characterization. Three dimensional structures for these proteins were not available as yet at PDB. Therefore, homology mod.. View More»
DOI:
10.4172/jpb.1000134