Journal of Proteomics & Bioinformatics
Open Access
ISSN: 0974-276X
ISSN: 0974-276X
Karim Chahed
Tunisia
Research Article
Proteomic Analysis of Human Breast Cancer: New Technologies and Clinical Applications for Biomarker Profiling
Author(s): Bechr Hamrita, Hela ben nasr, Karim Chahed, Maria Kabbage and Lotfi ChouchaneBechr Hamrita, Hela ben nasr, Karim Chahed, Maria Kabbage and Lotfi Chouchane
Breast cancer is the most diagnosed cancer in women, accounting for approximately 40,000 deaths annually in the USA. In Tunisia, the incidence of breast cancer is approximately 19 new cases per 100,000 women per year. Significant advances have been made in the areas of detection and treatment, but a significant number of breast cancers are detected late. The enormous progress in proteomics, enabled by recent advances in MS (mass spectrometry), has brought protein analysis back into the limelight of breast cancer research, reviving old areas as well as opening new fields of study like early detection, prognosis, diagnosis, and therapy. Several proteomics technologies have been used to uncover molecular mechanisms associated with breast carcinoma at the global level to discover protein patterns that distinguish disease and disease-free states with high .. View More»
DOI:
10.4172/jpb.1000126