Journal of Proteomics & Bioinformatics
Open Access

K. Manikandakumar

Publications

• Research Article
  Classification of Protein Structural Classes using Isoluecine and Lysine Amino Acids
  Author(s): K. Manikandakumar, K. Gokul Raj, R. Srikumar and S. Muthukumaran K. Manikandakumar, K. Gokul Raj, R. Srikumar and S. Muthukumaran
  
  Exploration of the structural organisation of proteins is essential for understanding of the mechanisms of protein folding and function, and for insights into protein evolution. Protein structure comparison can provide useful information on the biological function of a protein and can imply evolutionary relationships between proteins with low sequence similarity. Structural biology and structural genomics are expected to produce many three-dimensional protein structures in the near future. Each new structure raises questions about its function and evolution. Correct functional and evolutionary classification of a new structure is difficult for distantly related proteins and error-prone using simple statistical scores based on sequence or structure similarity. The objective of this study is to classifying the protein structural classes using key amino acid residues as .. View More»
  DOI: 10.4172/jpb.1000143

  Abstract PDF

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