Pediatrics & Therapeutics
Open Access
ISSN: 2161-0665
+44 1478 350008
ISSN: 2161-0665
+44 1478 350008
Jayakumar Chandrasekhar
Amrita Institute of Medical Sciences and Research Centre,
Ponekkara, Kochi, Kerala, 682024
India
Research Article
Treatment Effect of Probiotic Bacillus Clausii on Neonatal Jaundice in Late Preterm and Term Newborn Babies: An Experimental Study
Author(s): Jayakumar Chandrasekhar, Thomas Panikasseril Varghese, Anjana Gopi, Manu Raj, Remya Sudevan and Haripriya JayakumarJayakumar Chandrasekhar, Thomas Panikasseril Varghese, Anjana Gopi, Manu Raj, Remya Sudevan and Haripriya Jayakumar
Objective: To evaluate the effect of prophylactic probiotic Bacillus clausii treatment on the need and duration of phototherapy in new born babies. Design: Open labeled clinical trial. Setting: Level II obstetric ward of a teaching hospital in Southern India. Participants: A total of 1043 babies with a gestational age of more than 35 weeks were enrolled in the study. There were 510 babies in the probiotic Bacillus clausii intervention group and 533 babies in the control group. Intervention: Intervention group babies < 37 weeks received 2 ml of Bacillus clausii (2.5 ml for those >37 weeks) twice a day for 3 days. Main outcome measure: The outcome measures were (i) Need of phototherapy and (ii) Duration of phototherapy. Results: A total of 32 babies in control group and 17 in intervention group required phototherapy. This difference in need for phototh.. View More»
DOI:
10.4172/2161-0665.1000326