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Journal of Proteomics & Bioinformatics

Journal of Proteomics & Bioinformatics
Open Access

ISSN: 0974-276X

Huseyin Seker

Publications
  • Research Article
    Digital Signal Processing Techniques:Calculating Biological Functionalities
    Author(s): Norbert Nwankwo and Huseyin SekerNorbert Nwankwo and Huseyin Seker

    Calculating Biological functionalities of proteins and presenting them numerically is an approach that will benefit the designing of drugs and vaccines. For example, potency of vaccines is known to be measured in terms of specificity, which is determined by bio-recognition (affinity), and sensitivity. Calculating the bio-recognition of peptides employed in the design of vaccines by means of procedures like the Digital Signal Processing (DSP) techniques rather than clinical experimentations not only gives room for the manipulation of the amino acids sequences of the peptides but also helps determine the degree of specificity of the antibody generated, hence the potency of the vaccine produced. This also provides opportunity for optimatization of the peptides for the desired biological characteristics. Also comparing the potency of peptide-based drugs through calculation of their biolog.. View More»
    DOI: 10.4172/jpb.1000199

    Abstract PDF

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